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SB-265610

Product Specifications

CAS Number

211096-49-0

Target

CXCR

Related Pathways

GPCR/G Protein, Autophagy, Immunology/Inflammation

Purity

0.995

Bioactivity

SB-265610 (GSK-CXCR2) is a nonpeptide and allosteric CXCR2 antagonist. SB-265610 blocks rat cytokine-induced neutrophil chemoattractant-1 (CINC-1) -induced calcium mobilization and neutrophil chemotaxis (IC50s: 3.7 nM and 70 nM, respectively) .

Smiles

Brc1ccccc1NC(=O)Nc1ccc(C#N)c2nn[nH]c12

Molecular Formula

C14H9BrN6O

Molecular Weight

357.16

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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