SB-265610
Product Specifications
CAS Number
211096-49-0
Target
CXCR
Related Pathways
GPCR/G Protein, Autophagy, Immunology/Inflammation
Purity
0.995
Bioactivity
SB-265610 (GSK-CXCR2) is a nonpeptide and allosteric CXCR2 antagonist. SB-265610 blocks rat cytokine-induced neutrophil chemoattractant-1 (CINC-1) -induced calcium mobilization and neutrophil chemotaxis (IC50s: 3.7 nM and 70 nM, respectively) .
Smiles
Brc1ccccc1NC(=O)Nc1ccc(C#N)c2nn[nH]c12
Molecular Formula
C14H9BrN6O
Molecular Weight
357.16
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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