SAICAR

3031-95-6

Endogenous Metabolite, Others

Others, Metabolism

SAICAR, an intermediate of de novo purine nucleotide biosynthesis, selectively activates pyruvate kinase isoform M2 (PKM2) with an EC50 of 0.3 mM.

NC=1N(C=NC1C(N[C@@H](CC(O)=O)C(O)=O)=O)[C@@]2(O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]2O)[H]

C13H19N4O12P

454.28

Ice Packs

-20°C