RWJ-67657

Product Specifications

CAS Number

215303-72-3

Target

P38 MAPK

Related Pathways

MAPK

Purity

0.9966

Bioactivity

RWJ-67657 (JNJ 3026582) is an orally active, selective p38? and p38? MAPK inhibitor (IC50s: 1 and 11 ?M, respectively), with no activity at p38? and p38?, and demonstrates cardioprotective effects.

Smiles

OCCC#Cc1nc(c(-c2ccncc2)n1CCCc1ccccc1)-c1ccc(F)cc1

Molecular Formula

C27H24FN3O

Molecular Weight

425.5

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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