RWJ-67657
Product Specifications
CAS Number
215303-72-3
Target
P38 MAPK
Related Pathways
MAPK
Purity
0.9966
Bioactivity
RWJ-67657 (JNJ 3026582) is an orally active, selective p38α and p38β MAPK inhibitor (IC50s: 1 and 11 μM, respectively), with no activity at p38γ and p38δ, and demonstrates cardioprotective effects.
Smiles
OCCC#Cc1nc(c(-c2ccncc2)n1CCCc1ccccc1)-c1ccc(F)cc1
Molecular Formula
C27H24FN3O
Molecular Weight
425.5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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TRIAD3A (E3 Ubiquitin Ligase TRIAD3A, E3 ubiquitin-protein ligase RNF216, RING finger protein 216, Ubiquitin-conjugating enzyme 7-interacting protein 1, UbcM4-interacting protein 83, Triad domain-containing protein 3, Rnf216, Triad3, Ubce7ip1, Uip83, Zin)
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