Rottlerin
Product Specifications
CAS Number
82-08-6
Target
HIV Protease, Apoptosis, CaMK, Autophagy, PKC, PKA
Related Pathways
Neuroscience, Apoptosis, Autophagy, Microbiology/Virology, Cytoskeletal Signaling, Chromatin/Epigenetic, Proteases/Proteasome, Tyrosine Kinase/Adaptors
Purity
0.9944
Bioactivity
Rottlerin (NSC-56346) is a natural product purified from Mallotus Philippinensis and is a specific PKC inhibitor (IC50: PKCδ of 3-6 μM, PKCα, β, γ of 30-42 μM, PKCε, η, ζ of 80-100 μM) . Rottlerin causes apoptosis via caspase 3 activation.
Smiles
CC(=O)c1c(O)c(C)c(O)c(Cc2c(O)c3C=CC(C)(C)Oc3c(C(=O)\C=C\c3ccccc3)c2O)c1O
Molecular Formula
C30H28O8
Molecular Weight
516.54
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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