Roniciclib
Product Specifications
CAS Number
1223498-69-8
Target
CDK
Related Pathways
Cell Cycle/Checkpoint
Purity
0.9884
Bioactivity
Roniciclib (BAY 1000394) is a potent pan-CDK inhibitor and a novel oral cytotoxic agent. Roniciclib inhibits the activity of cell-cycle CDKs CDK1, CDK2, CDK3, CDK4, and of transcriptional CDKs CDK7 and CDK9 with IC (50) values in the range between 5 and 25 nmol/L.
Smiles
C[C@@H](O)[C@@H](C)Oc1nc(Nc2ccc(cc2)[S@](=N)(=O)C2CC2)ncc1C(F)(F)F
Molecular Formula
C18H21F3N4O3S
Molecular Weight
430.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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