Rodatristat ethyl
Product Specifications
CAS Number
1673571-51-1
Target
Hydroxylase, 5-HT Receptor
Related Pathways
Neuroscience, GPCR/G Protein, Metabolism
Bioactivity
Rodatristat ethyl (KAR5585) is a groundbreaking, orally active, and potent inhibitor of tryptophan hydroxylase 1 (TPH1) that significantly reduces 5-hydroxytryptamine (5-HT) levels and decreases pulmonary arterial hypertension (PAH) at low concentrations.
Smiles
C(OCC)(=O)[C@@H]1CC2(CCN(CC2)C=3C=C(O[C@@H](C(F)(F)F)C4=C(C=C(Cl)C=C4)C5=CC=CC=C5)N=C(N)N3)CN1
Molecular Formula
C29H31ClF3N5O3
Molecular Weight
590.04
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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