Ro 90-7501
Product Specifications
CAS Number
293762-45-5
Target
ATM/ATR|||Gamma-secretase|||Beta Amyloid|||Phosphatase|||Apoptosis
Related Pathways
Apoptosis|||Metabolism|||Stem Cells|||DNA Damage/DNA Repair|||Proteases/Proteasome|||Neuroscience|||PI3K/Akt/mTOR signaling
Purity
0.998
Bioactivity
Ro 90-7501 is an amyloid ?42 (A?42) protofibrillar and TPR-dependent PP5 inhibitor, a novel radiosensitizer for cervical cancer cells, which inhibits ATM phosphorylation, promotes apoptosis, and induces cell-cycle arrest. Ro 90-7501 also exhibits antiviral activity and potential anticancer activity by inhibiting ATM phosphorylation and DNA repair, and by inhibiting HCMV.
Smiles
NC1=CC=C(C=C1)C1=NC2=C(N1)C=C(C=C2)C1=NC2=C(N1)C=C(N)C=C2
Molecular Formula
C20H16N6
Molecular Weight
340.38
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Product Datasheet
https://www.targetmol.com/attachment/DataSheet/6458857B-AF07-4E26-9437-2203CBE7E8BB/T16773
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1396368-01 0.5 mg (E-Coli)
Recombinant Mouse Slit homolog 3 protein (Slit3) , partial
Ask
View Details 
MBS1396368-02 0.05 mg (Baculovirus)
Recombinant Mouse Slit homolog 3 protein (Slit3) , partial
Ask
View Details 
MBS1396368-03 0.05 mg (Mammalian-Cell)
Recombinant Mouse Slit homolog 3 protein (Slit3) , partial
Ask
View Details