Ro 90-7501
Product Specifications
CAS Number
293762-45-5
Target
ATM/ATR|||Gamma-secretase|||Beta Amyloid|||Phosphatase|||Apoptosis
Related Pathways
Apoptosis|||Metabolism|||Stem Cells|||DNA Damage/DNA Repair|||Proteases/Proteasome|||Neuroscience|||PI3K/Akt/mTOR signaling
Purity
0.998
Bioactivity
Ro 90-7501 is an amyloid ?42 (A?42) protofibrillar and TPR-dependent PP5 inhibitor, a novel radiosensitizer for cervical cancer cells, which inhibits ATM phosphorylation, promotes apoptosis, and induces cell-cycle arrest. Ro 90-7501 also exhibits antiviral activity and potential anticancer activity by inhibiting ATM phosphorylation and DNA repair, and by inhibiting HCMV.
Smiles
NC1=CC=C(C=C1)C1=NC2=C(N1)C=C(C=C2)C1=NC2=C(N1)C=C(N)C=C2
Molecular Formula
C20H16N6
Molecular Weight
340.38
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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