RO-5963
Product Specifications
CAS Number
1416663-77-8
Target
MDM-2/p53, E1/E2/E3 Enzyme, Mdm2, p53
Related Pathways
Apoptosis, Ubiquitination
Purity
0.9936
Bioactivity
RO-5963 is a dual inhibitor of p53-MDM2 and p53-MDMX (IC50s: ~17 nM and ~24 nM, respectively) .
Smiles
C(C(NC(CO)CO)=O)(N1C(=O)C(=CC=2C=3C(NC2)=C(C)C(Cl)=CC3)NC1=O)C4=CC(F)=C(F)C=C4
Molecular Formula
C24H21ClF2N4O5
Molecular Weight
518.9
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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