RO-5963

1416663-77-8

MDM-2/p53, E1/E2/E3 Enzyme, Mdm2, p53

Apoptosis, Ubiquitination

0.9936

RO-5963 is a dual inhibitor of p53-MDM2 and p53-MDMX (IC50s: ~17 nM and ~24 nM, respectively) .

C(C(NC(CO)CO)=O)(N1C(=O)C(=CC=2C=3C(NC2)=C(C)C(Cl)=CC3)NC1=O)C4=CC(F)=C(F)C=C4

C24H21ClF2N4O5

518.9

Ice Packs

-20°C