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Rebeccamycin

Product Specifications

CAS Number

93908-02-2

Target

ADC Cytotoxin, Antibiotic, Topoisomerase

Related Pathways

Microbiology/Virology, DNA Damage/DNA Repair, Antibody-drug Conjugate/ADC Related

Bioactivity

Rebeccamycin is an antitumor antibiotic+ inhibits DNA topoisomerase I. Rebeccamycin appears to exert its primary antineoplastic effect by poisoning topoisomerase I. It also has a negligible effect on protein kinase C and topoisomerase II.

Smiles

O=C1C2=C3C(N(C=4C3=CC=CC4Cl)[C@@]5(O[C@H](CO)[C@@H](OC)[C@H](O)[C@H]5O)[H])=C6C(=C2C(=O)N1)C=7C(N6)=C(Cl)C=CC7

Molecular Formula

C27H21Cl2N3O7

Molecular Weight

570.38

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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