Rebeccamycin
Product Specifications
CAS Number
93908-02-2
Target
ADC Cytotoxin|||Antibiotic|||Topoisomerase
Related Pathways
Microbiology/Virology|||DNA Damage/DNA Repair|||Antibody-drug Conjugate/ADC Related
Bioactivity
Rebeccamycin is an antitumor antibiotic+ inhibits DNA topoisomerase I. Rebeccamycin appears to exert its primary antineoplastic effect by poisoning topoisomerase I. It also has a negligible effect on protein kinase C and topoisomerase II.
Smiles
O=C1C2=C3C(N(C=4C3=CC=CC4Cl)[C@@]5(O[C@H](CO)[C@@H](OC)[C@H](O)[C@H]5O)[H])=C6C(=C2C(=O)N1)C=7C(N6)=C(Cl)C=CC7
Molecular Formula
C27H21Cl2N3O7
Molecular Weight
570.38
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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