R 59-022
Product Specifications
CAS Number
93076-89-2
Target
PKC|||5-HT Receptor
Related Pathways
GPCR/G Protein|||Cytoskeletal Signaling|||Neuroscience|||Chromatin/Epigenetic
Purity
0.9855
Bioactivity
R 59-022 (DKGI-I) is a diacylglycerol kinase (DGK) inhibitor and a 5-HT Receptor antagonist that blocks filovirus internalization in host cells. R 59-022 activates protein kinase C (PKC), inhibits intestinal smooth muscle contractility, and enhances O2- production induced by 1-oleoyl-2-acetylglycerol.
Smiles
O=C1C(=C(N=C2SC=CN21)C)CCN3CCC(=C(C=4C=CC=CC4)C5=CC=C(F)C=C5)CC3
Molecular Formula
C27H26FN3OS
Molecular Weight
459.58
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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