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R-268712

Product Specifications

CAS Number

879487-87-3

Target

ALK, TGF-beta/Smad

Related Pathways

Stem Cells, Angiogenesis, Tyrosine Kinase/Adaptors

Purity

0.9977

Bioactivity

R-268712 is a specific activin receptor-like kinase 5 (ALK5) inhibitor (IC50 of 2.5 nM) . It is also an orally active transforming growth factor-β type I receptor inhibitor.

Smiles

Cc1cccc(n1)-c1n[nH]cc1-c1ccc(F)c(c1)-c1cnn(CCO)c1

Molecular Formula

C20H18FN5O

Molecular Weight

363.39

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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