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Pyrazofurin

Product Specifications

CAS Number

30868-30-5

Target

Others, SARS-CoV, DNA/RNA Synthesis, HIV Protease, Influenza Virus, Antibiotic

Related Pathways

DNA Damage/DNA Repair, Cell Cycle/Checkpoint, Others, Microbiology/Virology, Proteases/Proteasome

Bioactivity

Pyrazofurin is a pyrimidine nucleoside analogue, inhibits cell proliferation and DNA synthesis in cells by inhibiting UMP synthase. Pyrazofurin is a sensitive orotate-phosphoribosyltransferase inhibitor (IC50s between 0.06-0.37 μM in the cell lines Hep-2, HNSCC-14B, and HNSCC-14C) .

Smiles

NC(=O)c1n[nH]c([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c1O

Molecular Formula

C9H13N3O6

Molecular Weight

259.22

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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