Pyrazofurin
Product Specifications
CAS Number
30868-30-5
Target
Others, SARS-CoV, DNA/RNA Synthesis, HIV Protease, Influenza Virus, Antibiotic
Related Pathways
DNA Damage/DNA Repair, Cell Cycle/Checkpoint, Others, Microbiology/Virology, Proteases/Proteasome
Bioactivity
Pyrazofurin is a pyrimidine nucleoside analogue, inhibits cell proliferation and DNA synthesis in cells by inhibiting UMP synthase. Pyrazofurin is a sensitive orotate-phosphoribosyltransferase inhibitor (IC50s between 0.06-0.37 μM in the cell lines Hep-2, HNSCC-14B, and HNSCC-14C) .
Smiles
NC(=O)c1n[nH]c([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c1O
Molecular Formula
C9H13N3O6
Molecular Weight
259.22
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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