Pyr10
Product Specifications
CAS Number
1315323-00-2
Target
TRP/TRPV Channel
Related Pathways
Membrane transporter/Ion channel
Purity
0.997
Bioactivity
Pyr10 is a pyrazole derivative and a selective TRP cation 3 inhibitor that distinguishes between receptor-operated TRPC3 and native stromal interaction molecule 1 (STIM1) /Orai1 channels. Pyr10 inhibits Ca2+ influx in carbachol-stimulated TRPC3-transfected HEK293 cells (IC50: 0.72 μM) and has an IC50 of 13.08 μM for store-operated Ca2+ entry in BRL-2H3 cells.
Smiles
Cc1ccc(cc1)S(=O)(=O)Nc1ccc(cc1)-n1nc(cc1C(F)(F)F)C(F)(F)F
Molecular Formula
C18H13F6N3O2S
Molecular Weight
449.37
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
HK205522 1 Kit
CD31 (PECAM1) Human qPCR Template Standard (NM_000442)
Sign In for Pricing
View Details 
HI935001 1 Each
Karl Fischer Coulometric titrator with diaphragm generator, 230V
Sign In for Pricing
View Details