PTC-028

Product Specifications

CAS Number

1782970-28-8

Target

Apoptosis|||BMI-1

Related Pathways

DNA Damage/DNA Repair|||Apoptosis|||Cell Cycle/Checkpoint

Purity

0.9825

Bioactivity

PTC-028 selectively suppresses cancer cells whereas normal cells remain unaffected. PTC-028 is an orally bioavailable inhibitor of stem cell factor BMI-1 in ovarian cancer. The depletion of BMI-1 by PTC-028 causes caspase-mediated apoptosis.

Smiles

Cc1nc2cc(F)c(F)cc2n1-c1cncc(Nc2ccc(cc2)C(F)(F)F)n1

Molecular Formula

C19H12F5N5

Molecular Weight

405.32

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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