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PS210

Product Specifications

CAS Number

1221962-86-2

Target

PDK

Related Pathways

PI3K/Akt/mTOR signaling

Purity

0.9978

Bioactivity

PS210 is a potent and selective activator of PDK1 (Kd: 3 μM), specifically targeting the PIF-binding pocket of PDK1 without affecting other protein kinases such as S6K, PKB/Akt, or GSK3. Its prodrug, PS423, serves as a substrate-selective inhibitor of PDK1 in cells, inhibiting the phosphorylation and activation of S6K.

Smiles

OC(=O)C(C(CC(=O)c1ccc(cc1)C(F)(F)F)c1ccccc1)C(O)=O

Molecular Formula

C19H15F3O5

Molecular Weight

380.31

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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