Propargyl-PEG4-acid
Product Specifications
CAS Number
1415800-32-6
Target
Others, PROTAC Linker
Related Pathways
Others, PROTAC
Bioactivity
Propargyl-PEG4-acid is a PEG-based PROTAC linker used in the synthesis of BTK-IAP PROTACs, including Ibrutinib-based PROTAC 2 and its analogue PROTAC 3. PROTAC 3 induces BTK degradation with a DC50 of 200 nM in THP-1 cells[1].
Smiles
C(OCCOCCOCC#C)COCCC(O)=O
Molecular Formula
C12H20O6
Molecular Weight
260.28
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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