SNT-207707
SNT-207707 is a selective, potent and orally active melanocortin MC-4 receptor antagonist with an IC50 of 8 nM (binding) and 5 nM (function) on the MC-4 receptor.
Product Specifications
CAS Number
[1064662-40-3]
UNSPSC
12352005
Target
Melanocortin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Cancer; Metabolic Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/SNT-207707.html
Purity
99.54
Solubility
DMSO : ≥ 250 mg/mL
Smiles
O=C(C1=CN2C(C=C1)=NC(C3=CC=C(C#N)C=C3)=C2CCCN4CCCC4)N(CCC(C)C)CCC(C)C.Cl
Molecular Formula
C32H44ClN5O
Molecular Weight
550.18
References & Citations
[1]Weyermann P, et al. Orally available selective melanocortin-4 receptor antagonists stimulate food intake and reduce cancer-induced cachexia in mice. PLoS One. 2009;4 (3) :e4774.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MC4R
Available Sizes
Curated Selection
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