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SNT-207707

SNT-207707 is a selective, potent and orally active melanocortin MC-4 receptor antagonist with an IC50 of 8 nM (binding) and 5 nM (function) on the MC-4 receptor.

Product Specifications

CAS Number

[1064662-40-3]

UNSPSC

12352005

Target

Melanocortin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Cancer-programmed cell death

Field of Research

Cancer; Metabolic Disease; Endocrinology

Assay Protocol

https://www.medchemexpress.com/SNT-207707.html

Purity

99.54

Solubility

DMSO : ≥ 250 mg/mL

Smiles

O=C(C1=CN2C(C=C1)=NC(C3=CC=C(C#N)C=C3)=C2CCCN4CCCC4)N(CCC(C)C)CCC(C)C.Cl

Molecular Formula

C32H44ClN5O

Molecular Weight

550.18

References & Citations

[1]Weyermann P, et al. Orally available selective melanocortin-4 receptor antagonists stimulate food intake and reduce cancer-induced cachexia in mice. PLoS One. 2009;4 (3) :e4774.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

MC4R

Available Sizes

Curated Selection

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