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Crizotinib

Product Specifications

CAS Number

877399-52-5

Target

C-Met/HGFR, Autophagy, ROS Kinase, ALK, ROS

Related Pathways

Autophagy, Angiogenesis, Immunology/Inflammation, Tyrosine Kinase/Adaptors

Purity

0.9987

Bioactivity

Crizotinib (PF-02341066) is an ATP-competitive small-molecule tyrosine kinase inhibitor of c-MET (IC50: 8 nM) and ALK (IC50: 20 nM) receptors.

Smiles

O([C@H](C)C1=C(Cl)C(F)=CC=C1Cl)C2=CC(C3=CN(N=C3)C4CCNCC4)=CN=C2N

Molecular Formula

C21H22Cl2FN5O

Molecular Weight

450.34

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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