Crizotinib
Product Specifications
CAS Number
877399-52-5
Target
C-Met/HGFR, Autophagy, ROS Kinase, ALK, ROS
Related Pathways
Autophagy, Angiogenesis, Immunology/Inflammation, Tyrosine Kinase/Adaptors
Purity
0.9987
Bioactivity
Crizotinib (PF-02341066) is an ATP-competitive small-molecule tyrosine kinase inhibitor of c-MET (IC50: 8 nM) and ALK (IC50: 20 nM) receptors.
Smiles
O([C@H](C)C1=C(Cl)C(F)=CC=C1Cl)C2=CC(C3=CN(N=C3)C4CCNCC4)=CN=C2N
Molecular Formula
C21H22Cl2FN5O
Molecular Weight
450.34
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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