Propargyl-PEG1-acid
Product Specifications
CAS Number
55683-37-9
Target
PROTAC Linker|||Others
Related Pathways
Others|||PROTAC
Bioactivity
Propargyl-PEG1-acid, a PEG-based PROTAC linker, enables the synthesis of BTK-CRBN PROTACs, specifically Ibrutinib-based PROTAC 4 and PROTAC 5. At a concentration of 10 ?M, PROTAC 5 facilitates the degradation of BTK and induces the degradation of CSK, LYN, and LAT2[1].
Smiles
OC(=O)CCOCC#C
Molecular Formula
C6H8O3
Molecular Weight
128.13
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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