Pralnacasan
Product Specifications
CAS Number
192755-52-5
Target
Caspase, Others
Related Pathways
Others, Proteases/Proteasome, Apoptosis
Bioactivity
Pralnacasan inhibits proinflammatory cytokines IL-18, IL-1β , and IFN-γ. Pralnacasan is an effective, non-peptide, and orally active interleukin-1β converting enzyme inhibitor (Ki: 1.4 nM) . Pralnacasan has the potential for osteoarthritis and rheumatoid arthritis treatment.
Smiles
CCO[C@@H]1OC(=O)C[C@@H]1NC(=O)[C@@H]1CCCN2N1C(=O)[C@H](CCC2=O)NC(=O)c1nccc2ccccc12
Molecular Formula
C26H29N5O7
Molecular Weight
523.54
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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