Praliciguat
Product Specifications
CAS Number
1628730-49-3
Target
Guanylate cyclase
Related Pathways
GPCR/G Protein
Purity
0.9905
Bioactivity
Praliciguat (IW-1973) stimulates sGC in HEK-293 cells (EC50: 197 nM) . Praliciguat is an effective and orally active soluble guanylate cyclase stimulator. It also enhances NO signaling and acts as a vasodilator.
Smiles
OC(CNc1nc(ncc1F)-c1cc(-c2ccon2)n(Cc2ccccc2F)n1)(C(F)(F)F)C(F)(F)F
Molecular Formula
C21H14F8N6O2
Molecular Weight
534.36
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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