PQR530
Product Specifications
CAS Number
1927857-61-1
Target
MTOR, PI3K
Related Pathways
PI3K/Akt/mTOR signaling
Purity
0.9978
Bioactivity
PQR530 is a highly potent dual pan-PI3K/mTORC1/2 inhibitor. PQR530 inhibited protein kinase B (PKB, pSer473) and ribosomal protein S6 (pS6, pSer235/236) phosphorylation with IC50 values of 0.07 μM. It also showing antitumor activity.
Smiles
C[C@H]1COCCN1c1nc(nc(n1)-c1cnc(N)cc1C(F)F)N1CCOCC1
Molecular Formula
C18H23F2N7O2
Molecular Weight
407.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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