PNU-101603

PNU-101603 is a sulfoxide metabolite of Sutezolid (HY-10392) . PNU-101603 alone or combined with SQ109 (HY-14989) shows excellent activity against Mycobacterium tuberculosis (MTB), as well as against agent-susceptible and multidrug-resistant TB[1][2].

Product Specifications

CAS Number

[168828-60-2]

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/pnu-101603.html

Purity

98.82

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC(NC[C@H]1CN(C2=CC=C(N3CCS(CC3)=O)C(F)=C2)C(O1)=O)=O

Molecular Formula

C16H20FN3O4S

Molecular Weight

369.41

References & Citations

[1]Reddy VM, et al. SQ109 and PNU-100480 interact to kill Mycobacterium tuberculosis in vitro. J Antimicrob Chemother. 2012 May;67 (5) :1163-6. |[2]Barbachyn MR, et al. Identification of a novel oxazolidinone (U-100480) with potent antimycobacterial activity. J Med Chem. 1996 Feb 2;39 (3) :680-5.