PNU-101603
Product Specifications
UNSPSC Description
PNU-101603 is a sulfoxide metabolite of Sutezolid (HY-10392). PNU-101603 alone or combined with SQ109 (HY-14989) shows excellent activity against Mycobacterium tuberculosis (MTB), as well as against agent-susceptible and multidrug-resistant TB[1][2].
Target Antigen
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/pnu-101603.html
Purity
98.83
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(NC[C@H]1CN(C2=CC=C(N3CCS(CC3)=O)C(F)=C2)C(O1)=O)=O
Molecular Weight
369.41
References & Citations
[1]Reddy VM, et al. SQ109 and PNU-100480 interact to kill Mycobacterium tuberculosis in vitro. J Antimicrob Chemother. 2012 May;67(5):1163-6. |[2]Barbachyn MR, et al. Identification of a novel oxazolidinone (U-100480) with potent antimycobacterial activity. J Med Chem. 1996 Feb 2;39(3):680-5.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-125941/PNU-101603-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-125941/PNU-101603-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
168828-60-2
Available Sizes
Curated Selection
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