PNU-101603
PNU-101603 is a sulfoxide metabolite of Sutezolid (HY-10392) . PNU-101603 alone or combined with SQ109 (HY-14989) shows excellent activity against Mycobacterium tuberculosis (MTB), as well as against agent-susceptible and multidrug-resistant TB[1][2].
Product Specifications
CAS Number
[168828-60-2]
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/pnu-101603.html
Purity
98.82
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(NC[C@H]1CN(C2=CC=C(N3CCS(CC3)=O)C(F)=C2)C(O1)=O)=O
Molecular Formula
C16H20FN3O4S
Molecular Weight
369.41
References & Citations
[1]Reddy VM, et al. SQ109 and PNU-100480 interact to kill Mycobacterium tuberculosis in vitro. J Antimicrob Chemother. 2012 May;67 (5) :1163-6. |[2]Barbachyn MR, et al. Identification of a novel oxazolidinone (U-100480) with potent antimycobacterial activity. J Med Chem. 1996 Feb 2;39 (3) :680-5.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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