Pozanicline
Product Specifications
CAS Number
161417-03-4
Target
AChR
Related Pathways
Neuroscience
Bioactivity
Pozanicline reverses nicotine withdrawal-induced cognitive deficits, may be an effective component of novel therapeutic strategies for nicotine addiction. Pozanicline selectively activate neuronal nicotinic acetylcholine receptor (nAChR) subtypes, is a novel cholinergic agent that is a partial agonist at α4β2 nAChRs (Ki=16 nM) . It shows high selectivity for α6β2 and α4α5β2 nAChR subtypes, the binding affinity (Ki, rat) for Pozanicline to [3H] cytisine sites is 16.7 nM .
Smiles
O(C[C@@H]1CCCN1)C2=C(C)N=CC=C2
Molecular Formula
C11H16N2O
Molecular Weight
192.26
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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