Picrotoxinin
Product Specifications
CAS Number
17617-45-7
Target
GABA Receptor, Chloride channel
Related Pathways
Membrane transporter/Ion channel, Neuroscience
Purity
0.9997
Bioactivity
Picrotoxinin is a blocker of chloride channel and a noncompetitive antagonist of GABAA with an IC50 of 1.15 μM for α1β2γ2L GABAA. Picrotoxinin shows convulsant properties.
Smiles
[H][C@@]12C[C@@]3(O)[C@]4([H])[C@H](C(C)=C)[C@@]([H])(OC4=O)[C@@]4([H])OC(=O)[C@]1(O2)[C@@]34C
Molecular Formula
C15H16O6
Molecular Weight
292.28
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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