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Picrotoxinin

Product Specifications

CAS Number

17617-45-7

Target

GABA Receptor, Chloride channel

Related Pathways

Membrane transporter/Ion channel, Neuroscience

Purity

0.9997

Bioactivity

Picrotoxinin is a blocker of chloride channel and a noncompetitive antagonist of GABAA with an IC50 of 1.15 μM for α1β2γ2L GABAA. Picrotoxinin shows convulsant properties.

Smiles

[H][C@@]12C[C@@]3(O)[C@]4([H])[C@H](C(C)=C)[C@@]([H])(OC4=O)[C@@]4([H])OC(=O)[C@]1(O2)[C@@]34C

Molecular Formula

C15H16O6

Molecular Weight

292.28

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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