PF-4693627
Product Specifications
CAS Number
1312815-93-2
Target
PGE Synthase|||Prostaglandin Receptor
Related Pathways
GPCR/G Protein|||Immunology/Inflammation
Bioactivity
PF-4693627 is an effective and selective microsomal prostaglandin E synthase-1 inhibitor (IC50=3 nM) . It is used for the treatment of inflammation caused by osteoarthritis (OA) and rheumatoid arthritis (RA) .
Smiles
ClC=1C=C2C(OC(=N2)N3CCC(C(N[C@@H]4C[C@@H](CO)CCC4)=O)CC3)=CC1C5=CC=C(Cl)C=C5
Molecular Formula
C26H29Cl2N3O3
Molecular Weight
502.43
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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