PF-4693627

Product Specifications

CAS Number

1312815-93-2

Target

PGE Synthase|||Prostaglandin Receptor

Related Pathways

GPCR/G Protein|||Immunology/Inflammation

Bioactivity

PF-4693627 is an effective and selective microsomal prostaglandin E synthase-1 inhibitor (IC50=3 nM) . It is used for the treatment of inflammation caused by osteoarthritis (OA) and rheumatoid arthritis (RA) .

Smiles

ClC=1C=C2C(OC(=N2)N3CCC(C(N[C@@H]4C[C@@H](CO)CCC4)=O)CC3)=CC1C5=CC=C(Cl)C=C5

Molecular Formula

C26H29Cl2N3O3

Molecular Weight

502.43

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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