PF-4191834
Product Specifications
CAS Number
1029317-21-2
Target
Lipoxygenase
Related Pathways
Metabolism
Purity
>99.99%
Bioactivity
PF-4191834 is a noniron chelating and non-redox inhibitor of the 5-Lipoxygenase (5-LOX) with an IC50 of 229 nM. PF-4191834 shows ~300-fold selectivity for 5-LOX over 12-LOX and 15-LOX and displays no activity toward the cyclooxygenase enzymes. PF-4191834
Smiles
Cn1nccc1-c1ccc(Sc2cccc(c2)C2(CCOCC2)C(N)=O)cc1
Molecular Formula
C22H23N3O2S
Molecular Weight
393.5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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