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PF-4191834

Product Specifications

CAS Number

1029317-21-2

Target

Lipoxygenase

Related Pathways

Metabolism

Purity

>99.99%

Bioactivity

PF-4191834 is a noniron chelating and non-redox inhibitor of the 5-Lipoxygenase (5-LOX) with an IC50 of 229 nM. PF-4191834 shows ~300-fold selectivity for 5-LOX over 12-LOX and 15-LOX and displays no activity toward the cyclooxygenase enzymes. PF-4191834

Smiles

Cn1nccc1-c1ccc(Sc2cccc(c2)C2(CCOCC2)C(N)=O)cc1

Molecular Formula

C22H23N3O2S

Molecular Weight

393.5

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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