PF-06446846 hydrochloride
Product Specifications
CAS Number
1632250-50-0
Target
Others
Related Pathways
Others
Purity
0.987
Bioactivity
PF-06446846 hydrochloride, an orally active and highly selective inhibitor, targets Proprotein Convertase Subtilisin/Kexin type 9 (PCSK9) translation by inducing ribosomal stalling at approximately codon 34, effectively suppressing PCSK9 expression.
Smiles
Cl.Clc1cccnc1N([C@@H]1CCCNC1)C(=O)c1ccc(cc1)-n1nnc2cccnc12
Molecular Formula
C22H20CIN7O.XHCl
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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