PF-06263276
Product Specifications
CAS Number
1421502-62-6
Target
Others, STAT, JAK
Related Pathways
Chromatin/Epigenetic, Tyrosine Kinase/Adaptors, JAK/STAT signaling, Angiogenesis, Others, Stem Cells
Bioactivity
PF-06263276 is an effective and selective inhibitor of pan-JAK. It also has IC50s of 2.2 nM, 23.1 nM, 59.9 nM and 29.7 nM for JAK1, JAK2, JAK3, and TYK2, respectively.
Smiles
CCc1cc(O)c(F)cc1-c1ccc2c(n[nH]c2c1)-c1nc2CCN(Cc2[nH]1)C(=O)c1cnc(cn1)N1CCCCC1
Molecular Formula
C31H31FN8O2
Molecular Weight
566.63
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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