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PF-06263276

Product Specifications

CAS Number

1421502-62-6

Target

Others, STAT, JAK

Related Pathways

Chromatin/Epigenetic, Tyrosine Kinase/Adaptors, JAK/STAT signaling, Angiogenesis, Others, Stem Cells

Bioactivity

PF-06263276 is an effective and selective inhibitor of pan-JAK. It also has IC50s of 2.2 nM, 23.1 nM, 59.9 nM and 29.7 nM for JAK1, JAK2, JAK3, and TYK2, respectively.

Smiles

CCc1cc(O)c(F)cc1-c1ccc2c(n[nH]c2c1)-c1nc2CCN(Cc2[nH]1)C(=O)c1cnc(cn1)N1CCCCC1

Molecular Formula

C31H31FN8O2

Molecular Weight

566.63

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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