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PF-05085727

Product Specifications

CAS Number

1415637-72-7

Target

PDE

Related Pathways

Metabolism

Bioactivity

PF-05085727 inhibits PDE2A >4,000-fold selectivity over PDE1 and PDE3-11. PF-05085727 is an effective, selective and brain penetrant inhibitor of cGMP-dependent PDE2A (IC50=2 nM) .

Smiles

Cn1ncc(-c2nn(C)c3ncnc(N4CCC4)c23)c1-c1ccc(cc1)C(F)(F)F

Molecular Formula

C20H18F3N7

Molecular Weight

413.4

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Frequently Asked Questions

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