PF-05085727
Product Specifications
CAS Number
1415637-72-7
Target
PDE
Related Pathways
Metabolism
Bioactivity
PF-05085727 inhibits PDE2A >4,000-fold selectivity over PDE1 and PDE3-11. PF-05085727 is an effective, selective and brain penetrant inhibitor of cGMP-dependent PDE2A (IC50=2 nM) .
Smiles
Cn1ncc(-c2nn(C)c3ncnc(N4CCC4)c23)c1-c1ccc(cc1)C(F)(F)F
Molecular Formula
C20H18F3N7
Molecular Weight
413.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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