PF-04991532

Product Specifications

CAS Number

1215197-37-7

Target

Glucokinase

Related Pathways

Metabolism

Purity

0.9999

Bioactivity

PF-04991532 is a hepatoselective glucokinase activator that reduces plasma glucose and AMP concentrations in the Goto-Kakizaki rat model, with human and rat EC50 values of 80 and 100 nM respectively.

Smiles

[C@H](CC1CCCC1)(C(NC2=CC=C(C(O)=O)C=N2)=O)N3C=C(C(F)(F)F)N=C3

Molecular Formula

C18H19F3N4O3

Molecular Weight

396.36

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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