PF-04991532
Product Specifications
CAS Number
1215197-37-7
Target
Glucokinase
Related Pathways
Metabolism
Purity
0.9999
Bioactivity
PF-04991532 is a hepatoselective glucokinase activator that reduces plasma glucose and AMP concentrations in the Goto-Kakizaki rat model, with human and rat EC50 values of 80 and 100 nM respectively.
Smiles
[C@H](CC1CCCC1)(C(NC2=CC=C(C(O)=O)C=N2)=O)N3C=C(C(F)(F)F)N=C3
Molecular Formula
C18H19F3N4O3
Molecular Weight
396.36
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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