Pelubiprofen
Product Specifications
CAS Number
69956-77-0
Target
NF-κB, IκB/IKK, MAPK, COX, NO Synthase
Related Pathways
Immunology/Inflammation, NF-κB, Neuroscience, MAPK
Purity
0.9969
Bioactivity
Pelubiprofen is an orally active, non-steroidal anti-inflammatory agent, a selective cyclooxygenase-2 (COX-2) inhibitor, which effectively reduces PGE (2) production by inhibiting COX activity. Pelubiprofen inhibits LPS-induced phosphorylation of IKK-β and transforming growth factor-β activated kinase-1 (TAK1) .
Smiles
C(\C1=CC=C(C(C(O)=O)C)C=C1)=C\2/C(=O)CCCC2
Molecular Formula
C16H18O3
Molecular Weight
258.31
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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