PD-118057
Product Specifications
CAS Number
313674-97-4
Target
Potassium Channel
Related Pathways
Membrane transporter/Ion channel
Purity
0.9997
Bioactivity
PD-118057 is a potent ether associated (hERG) potassium channel activator that shows no activity against hERG. PD-118057 inhibits the excitability of the membrane by activating the hERG channel. PD-118057 is a potential compound for the treatment of delayed repolarization in inherited or acquired long QT syndrome and congestive heart failure.
Smiles
OC(=O)c1ccccc1Nc1ccc(CCc2ccc(Cl)c(Cl)c2)cc1
Molecular Formula
C21H17Cl2NO2
Molecular Weight
386.27
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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