PBIT

Product Specifications

CAS Number

2514-30-9

Target

Histone Demethylase, Histone Methyltransferase

Related Pathways

Chromatin/Epigenetic

Purity

0.9995

Bioactivity

PBIT inhibits JARID1B histone demethylase (IC50 of about 3 μM) . PBIT also inhibits JARID1A and JARID1C (IC50s of 6 μM and 4.9 μM, respectively) . PBIT is a specific inhibitor of the Jumonji AT-rich Interactive Domain 1 (JARID1) enzymes .

Smiles

CC1=CC=C(C=C1)N1SC2=CC=CC=C2C1=O

Molecular Formula

C14H11NOS

Molecular Weight

241.31

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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