Penciclovir
Product Specifications
CAS Number
39809-25-1
Target
Antifection, HCV Protease, HSV
Related Pathways
Microbiology/Virology, Proteases/Proteasome
Purity
0.991
Bioactivity
Penciclovir (BRL 39123) is a Herpesvirus Nucleoside Analog DNA Polymerase Inhibitor. In HSV infected cells, penciclovir is phosphorylated by viral thymidine kinase and subsequently converted by cellular kinases into the active metabolite, penciclovir triphosphate, which competitively inhibits viral HSV polymerase by blocking deoxyguanosine triphosphate substrate binding. As a result, herpes viral DNA synthesis and replication are selectively inhibited.
Smiles
C(CC(CO)CO)N1C2=C(N=C1)C(=O)N=C(N)N2
Molecular Formula
C10H15N5O3
Molecular Weight
253.26
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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