Orvepitant maleate
Product Specifications
CAS Number
579475-24-4
Target
Neurokinin receptor
Related Pathways
Neuroscience|||GPCR/G Protein
Bioactivity
Orvepitant maleate is an effective, selective, and well-tolerated neurokinin-1 receptor (NK-1) antagonist (pKi: 10.2 for human neurokinin-1 receptor) . Orvepitant maleate has the potential for depressive disorder and chronic refractory cough (CRC) treatment. Orvepitant maleate can across the blood-brain barrier.
Smiles
OC(=O)\C=C/C(O)=O.[H][C@@]12CCC(=O)N1CCN(C2)[C@H]1CCN([C@H](C1)c1ccc(F)cc1C)C(=O)N(C)[C@H](C)c1cc(cc(c1)C(F)(F)F)C(F)(F)F
Molecular Formula
C35H39F7N4O6
Molecular Weight
744.7
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Product Datasheet
https://www.targetmol.com/attachment/DataSheet/2F33C33B-A6C0-4AFF-88D0-5AA4333BA916/T16406
Available Sizes
Curated Selection
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